ApexBio是生物研究用肽和實(shí)驗(yàn)室試劑的主要供應(yīng)商。我們?cè)诩?xì)胞凋亡，表觀遺傳學(xué)，癌癥生物學(xué)等研究領(lǐng)域擁有廣泛的產(chǎn)品線。Apexbio還提供定制服務(wù)，包括肽合成，抗體生產(chǎn)和分析開(kāi)發(fā)。

我們的焦點(diǎn)

我們致力于通過(guò)提供多肽和生物分析試劑來(lái)滿足研究界的需求，主要關(guān)注細(xì)胞凋亡和表觀遺傳學(xué)。

產(chǎn)品質(zhì)量

認(rèn)識(shí)到科學(xué)家工具與研究成功之間存在著千絲萬(wàn)縷的聯(lián)系，ApexBio對(duì)產(chǎn)品的質(zhì)量給予了為謹(jǐn)慎的關(guān)注。所有產(chǎn)品均按照嚴(yán)格的指導(dǎo)原則制造，并附有分析證書(shū)，HPLC，質(zhì)譜和HMNR數(shù)據(jù)。

技術(shù)支持

ApexBio的生物學(xué)家和化學(xué)家為我們的客戶提供廣泛的技術(shù)支持以使用這些產(chǎn)品。您可以期待我們的支持人員回答您的訂單和技術(shù)咨詢，提供個(gè)性化和周到的服務(wù)。

化學(xué)性質(zhì)

背景

有效和直接抑制JAK2酪氨酸激酶自身磷酸化，特異性抑制配體依賴性JAK2激活。用1μM化合物處理16小時(shí)可將JAK2酪氨酸自磷酸化水平降低至約50％，而50μM則幾乎可消除所有JAK2活性。在100μM時(shí)無(wú)細(xì)胞毒性。

00001. Cat.No                 .Product                                      NameInformation

00002. A8181                   (-)-JQ1BET                               bromodomain inhibitor

00003. B7679                 (R)-(+)-Etomoxir sodium salt            carnitine palmitoyltransferase I (CPT1) inhibitor

00004. B7718               (R)-PFI 2 hydrochloride                     SETD7 histone lysine methyltransferase inhibitor

00005. C4834                   (S)-PFI-2 (hydrochloride)             Negative control of (R)-PFI 2 hydrochloride

00006. A4510               1,2,3,4,5,6-HexabromocyclohexaneJ          AK2 tyrosine kinase inhibitor

00007. C4119              2',3',5'-triacetyl-5-Azacytidine   prodrug form of 5-azacytidine, a DNA methyltransferase inhibitor

00008. B5972               2,4-Pyridinedicarboxylic Acid                 Histone LSD inhibitor

00009. C4445                      2-D08                               Sumoylation inhibitor

00010. B5969                2-hexyl-4-Pentynoic Acid                 Potent and robust HDACs inhibitor

00011. A4188                  2-Methoxyestradiol (2-MeOE2)        Apoptotic, antiproliferative and antiangiogenic agen

• A8182         3-Deazaneplanocin A (DZNep) hydrochloride      SAHH and ENZ2 inhibitor
• A1905        3-Deazaneplanocin,DZNep             S-adenosylhomocysteine and EZH2 inhibitor
• C3552        4'-bromo-Resveratrol                        Sirt1 and Sirt3 inhibitor
• A4524         4-HQN                                       PARP inhibitor
• C4018         4-iodo-SAHA         class I and class II histone deacetylase (HDAC) inhibitor
• B4106       4SC-202                                  Class I HDAC inhibitor
• C3505       5-(N,N-dimethyl)-Amiloride (hydrochloride)      NHE1, NHE2, and NHE3 inhibitor
• A1907         5-Azacytidine                           DNA methyltransferase inhibitor.
• B4947        A 366                      G9a/GLP histone lysine methyltransferase inhibitor
• A4160        A-966492                                PARP-1/-2 inhibitor, highly potent

00001. B1182           ABC294640                           Sphingosine kinase 2 inhibitor,selective and competitive

00002. A3002         ABT-888 (Veliparib)                                      Potent PARP inhibitor

00003. B5936           ACY-241                                Selective and orally active HDAC6 inhibitor

00004. B6120          Adox                                          indirect methyltransferase inhibitor

00005. A4158         AG-14361                                     Potent PARP1 inhibitor

00006. B7323            AGK 2                                        SIRT2 inhibitor, potent and selective

00007. C5709               AGK7                                     cell-permeable, selective inhibitor of SIRT2

00008. B4713              AK-7                                   selective and brain-permeable SIRT2 inhibitor

00009. A4542            Alexidine dihydrochloride                                PTPMT1 inhibitor

00010. A4119               AMG-900                                           Aurora kinase inhibitor

上海起發(fā)實(shí)驗(yàn)試劑有限公司是實(shí)驗(yàn)試劑一站式采購(gòu)服務(wù)商

1：強(qiáng)大的進(jìn)口輻射能力，血清、抗體、耗材、大部分限制進(jìn)口品等。

2：產(chǎn)品種類(lèi)齊全，經(jīng)營(yíng)超過(guò)700多品牌，基本涵蓋所有生物實(shí)驗(yàn)試劑耗材。

3：提供加急服務(wù)，貨品一般1-2周到貨。

4：富有競(jìng)爭(zhēng)力的價(jià)格優(yōu)勢(shì)，絕大部分價(jià)格有優(yōu)勢(shì)。

5：多年積累良好的信譽(yù)，大部分客戶提供貨到付款服務(wù)。客戶包括清華、北大、交大、復(fù)旦、中山等100多所高校，ROCHE，阿斯利康、國(guó)藥、fisher等知藥企。

6：我們還是Santa,Advanced Biotechnologies Inc,Athens Research & Technology,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, Genebridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech；sysy,TriLink BioTechnologies,Inc；worthington-biochem,zyagen等幾十家國(guó)外公司授權(quán)代理。

7：我們還是invitrogen,qiagen,MiraiBioam,sigma;neb,roche,merck, rnd,BD, GE,pierce,BioLegend等知*批發(fā)，歡迎合作。